Package index • GeoTox

GeoTox S3 Object

Functions using a GeoTox object

GeoTox() plot(<GeoTox>): GeoTox S3 object

calculate_response(): Calculate response

compute_sensitivity(): Compute response sensitivity to parameter variation.

plot_sensitivity(): Plot results of sensitivity analysis.

sensitivity_analysis(): Perform sensitivity analysis

set_boundaries(): Set GeoTox boundaries

set_hill_params(): Set Hill parameters for a GeoTox object.

simulate_population(): Simulate population data

Simulate

Functions that perform Monte Carlo simulation

sample_Css(): Sample from pre-generated C_ss data

simulate_age(): Simulate ages

simulate_exposure(): Simulate external exposure

simulate_inhalation_rate(): Simulate inhalation rates

simulate_obesity(): Simulate obesity status

Calculate Functions

Functions that calculate various metrics

calc_concentration_response(): Calculate the mixture response from one of three different approaches: IA, GCA, or Hazard Quotient

calc_independent_action(): Independent Action

calc_internal_dose(): Calculate internal chemical dose

calc_invitro_concentration(): Calculate in vitro concentration

resp_quantiles(): Get response quantiles

Plot

Plotting functions

plot_exposure(): Plot exposure data.

plot_hill(): Plot Hill equation fits.

plot_resp(): Plot response data

Auxiliary

Auxillary and helper functions

fit_hill(): Fit 2- or 3-parameter Hill model

hill_conc(): Hill model concentration

hill_val(): Hill model response

get_fixed_age(): Get C_ss Data for Fixed Age

get_fixed_css(): Get Fixed C_ss Data

get_fixed_obesity(): Get C_ss Data for Fixed Obesity Status

get_fixed_other(): Get median C_ss Values

get_fixed_params(): Get C_ss Data for Fixed C_ss Generation Parameters

Datasets

Package datasets

geo_tox_data: GeoTox Data